acetogenesis

Acetogenesis is a process through which acetyl-CoA or acetic acid is produced by anaerobic bacteria through the reduction of via the Wood–Ljungdahl pathway. Other microbial processes that produce acetic acid (like certain types of fermentation or the oxidative breakdown of carbohydrates or ethanol by acetic acid bacteria) are not considered acetogenesis. The diverse bacterial species capable of acetogenesis are collectively called acetogens. Reduction of to acetic acid via the Wood–Ljungdahl pathway requires an electron source (e.g., H 2 , CO, formate, etc.). When acetogens are grown autotrophically, they synthesize acetic acid only through the Wood–Ljungdahl pathway; but when they are grown heterotrophically, they can produce additional acetic acid by oxidation of the carbon source (carbohydrates, organic acids, or alcohols). Once produced, acetyl-CoA can be incorporated into biomass or converted to acetic acid.

Acetogenesis is a process through which acetyl-CoA or acetic acid is produced by anaerobic bacteria through the reduction of via the Wood–Ljungdahl pathway. Other microbial processes that produce acetic acid (like certain types of fermentation or the oxidative breakdown of carbohydrates or ethanol by acetic acid bacteria) are not considered acetogenesis. The diverse bacterial species capable of acetogenesis are collectively called acetogens. Reduction of to acetic acid via the Wood–Ljungdahl pathway requires an electron source (e.g., H 2 , CO, formate, etc.). When acetogens are grown autotrophically, they synthesize acetic acid only through the Wood–Ljungdahl pathway; but when they are grown heterotrophically, they can produce additional acetic acid by oxidation of the carbon source (carbohydrates, organic acids, or alcohols). Once produced, acetyl-CoA can be incorporated into biomass or converted to acetic acid. ΔG° = −95 kJ/mol The conversion of one mole of glucose into three moles of acetic acid is also a thermodynamically favorable reaction: ΔG° = −310.9 kJ/mol However, what matters for the cell is how much ATP is generated. This depends on the substrate.

Text derived from https://en.wikipedia.org/w/index.php?oldid=1364962424 under CC BY-SA 4.0; modifications have been made.