APOBEC
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APOBEC ("apolipoprotein B mRNA editing enzyme, catalytic polypeptide") is a family of evolutionarily conserved cytidine deaminases.
APOBEC ("apolipoprotein B mRNA editing enzyme, catalytic polypeptide") is a family of evolutionarily conserved cytidine deaminases.
Family members
Human genes encoding members of the APOBEC protein family include: APOBEC1 APOBEC2 APOBEC3A APOBEC3B APOBEC3C APOBEC3D ("APOBEC3E" now refers to this) APOBEC3F APOBEC3G APOBEC3H APOBEC4 Activation-induced (cytidine) deaminase (AID)
Bibliography
Gupta, A., Gazzo, A., Selenica, P. et al., APOBEC3 mutagenesis drives therapy resistance in breast cancer, Nature Genetics (April 1, 2025)
Text derived from https://en.wikipedia.org/w/index.php?oldid=1334721777 under CC BY-SA 4.0; modifications have been made.