Lesson plan

Assembloid

An assembloid is a self-organizing three-dimensional system formed by the functional integration of multiple organoids or by combining organoids with specialized cell types or primary tissue explants. They are typically derived from induced pluripotent stem cells. Assembloids have been used to study cell migration, neural circuit assembly, neuro-immune interactions, metastasis, and other complex tissue processes. The method for fusing organoids was a simultaneous discovery in 2017 by three labs. The term assembloid was later coined to standardize terminology.

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Article summary

An assembloid is a self-organizing three-dimensional system formed by the functional integration of multiple organoids or by combining organoids with specialized cell types or primary tissue explants. They are typically derived from induced pluripotent stem cells. Assembloids have been used to study cell migration, neural circuit assembly, neuro-immune interactions, metastasis, and other complex tissue processes. The method for fusing organoids was a simultaneous discovery in 2017 by three labs. The term assembloid was later coined to standardize terminology.

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Discussion questions

  1. Summarise the article in your own words. Which single claim would you verify first, and why?
  2. Which claim in this article is most likely to be revised as the sources update? How would you check its current status?
  3. If two sources disagreed about one of these facts, what would you need in order to trust one over the other?

Bibliography

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Key claims and bibliography are generated from the same tracked claims and sources as the article page.