Lesson plan

BLTP1

Bridge-like lipid transfer protein family member 1 BLTP1 (previously known as KIAA1109) is a protein that in humans is encoded by the BLTP1 gene. This protein functions as a molecular bridge involved in the transport of lipids from the endoplasmic reticulum to phospholipid membranes. Other aliases included FSA (fragile site-associated) protein, MGC110967 and DKFZp781P0474. An ortholog of BLTP1 has been found in Drosophila, responsible for regulating synaptic vesicle recycling and certain brain related functions. Drosophila exhibiting mutated BLTP1 were unable to walk or stand upright for long periods and exhibited seizures, reminiscent of severe neurological defects. This led to it being given the name "Tweek", after a character in South Park.

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Article summary

Bridge-like lipid transfer protein family member 1 BLTP1 (previously known as KIAA1109) is a protein that in humans is encoded by the BLTP1 gene. This protein functions as a molecular bridge involved in the transport of lipids from the endoplasmic reticulum to phospholipid membranes. Other aliases included FSA (fragile site-associated) protein, MGC110967 and DKFZp781P0474. An ortholog of BLTP1 has been found in Drosophila, responsible for regulating synaptic vesicle recycling and certain brain related functions. Drosophila exhibiting mutated BLTP1 were unable to walk or stand upright for long periods and exhibited seizures, reminiscent of severe neurological defects. This led to it being given the name "Tweek", after a character in South Park.

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  3. If two sources disagreed about one of these facts, what would you need in order to trust one over the other?

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