Lesson plan

Bufuralol

Bufuralol is a potent beta-adrenoceptor antagonist with partial agonist activity. It is metabolized by CYP2D6. Most beta blockers are aryloxypropanolamine-based. In this rare exception, the benzofuran oxygen is part of a ring rather than derived from the epichlorohydrin precursor.

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Article summary

Bufuralol is a potent beta-adrenoceptor antagonist with partial agonist activity. It is metabolized by CYP2D6. Most beta blockers are aryloxypropanolamine-based. In this rare exception, the benzofuran oxygen is part of a ring rather than derived from the epichlorohydrin precursor.

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Discussion questions

  1. Summarise the article in your own words. Which single claim would you verify first, and why?
  2. Which claim in this article is most likely to be revised as the sources update? How would you check its current status?
  3. If two sources disagreed about one of these facts, what would you need in order to trust one over the other?

Bibliography

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Key claims and bibliography are generated from the same tracked claims and sources as the article page.