Lesson plan
CAB39
Calcium-binding protein 39 is a protein that in humans is encoded by the CAB39 gene. The protein encoded by this gene associates with STK11 ( S erine/ T hreonine K inase 11 ) and STRAD ( ST E20- R elated AD aptor protein). CAB39 enhances formation of STK11/STRAD complexes and stimulates STK11 catalytic activity. CAB39 may function as a scaffolding component of the STK11/STRAD complex and regulates STK11 activity and cellular localization.
Article summary
Calcium-binding protein 39 is a protein that in humans is encoded by the CAB39 gene. The protein encoded by this gene associates with STK11 ( S erine/ T hreonine K inase 11 ) and STRAD ( ST E20- R elated AD aptor protein). CAB39 enhances formation of STK11/STRAD complexes and stimulates STK11 catalytic activity. CAB39 may function as a scaffolding component of the STK11/STRAD complex and regulates STK11 activity and cellular localization.
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Discussion questions
- Summarise the article in your own words. Which single claim would you verify first, and why?
- Which claim in this article is most likely to be revised as the sources update? How would you check its current status?
- If two sources disagreed about one of these facts, what would you need in order to trust one over the other?
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