CD1B
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T-cell surface glycoprotein CD1b is a protein that in humans is encoded by the CD1B gene. CD1b belongs to group 1 of CD1 family of transmembrane glycoproteins. CD1 molecules are expressed on the surface of numerous different human antigen presenting cells (DCs, monocytes and some thymocytes). This specialised group of glycoproteins present self and non-self lipid-based antigens to specific αβ T-cells. CD1 molecules are structurally related to the major histocompatibility complex (MHC), belonging to MHC class I-like genes. The human CD1 locus is found on chromosome 1 and contains five nonpolymorphic genes (CD1a, CD1b, CD1c, CD1d and CD1e).
T-cell surface glycoprotein CD1b is a protein that in humans is encoded by the CD1B gene. CD1b belongs to group 1 of CD1 family of transmembrane glycoproteins. CD1 molecules are expressed on the surface of numerous different human antigen presenting cells (DCs, monocytes and some thymocytes). This specialised group of glycoproteins present self and non-self lipid-based antigens to specific αβ T-cells. CD1 molecules are structurally related to the major histocompatibility complex (MHC), belonging to MHC class I-like genes. The human CD1 locus is found on chromosome 1 and contains five nonpolymorphic genes (CD1a, CD1b, CD1c, CD1d and CD1e).
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