Cfap157
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Cilia and flagella associated protein 157 (CFAP157) also known as chromosome 9 open reading frame 117 (c9orf117) is a protein that in humans is encoded by the CFAP157 gene. CFAP157 gene is "specifically required during spermatogenesis for flagellum morphogenesis and sperm motility and may be required to suppress the formation of supernumerary axonemes and ensure a correct ultrastructure," according to UniProt.
Cilia and flagella associated protein 157 (CFAP157) also known as chromosome 9 open reading frame 117 (c9orf117) is a protein that in humans is encoded by the CFAP157 gene. CFAP157 gene is "specifically required during spermatogenesis for flagellum morphogenesis and sperm motility and may be required to suppress the formation of supernumerary axonemes and ensure a correct ultrastructure," according to UniProt.
Protein
There are 520 amino acids in CFAP157 in human. The protein is glutamine extremely rich, and glycine poor. The protein is quite neutral with the isoelectric point at pH 7.4. The average mass of the protein is estimated to be 60,531.748 Da, and the absorption coefficient is estimated to be 25,440 M −1 cm −1 . CFAP157 is primarily composed of α-helices, and there is no transmembrane helix. The protein structure making program called Phyre is used to create the predicted structure of CFAP157.
Homology
There is no known paralog for CFAP157 in human. CFAP157 has numerous orthologs. The following table contains some of orthologs including human, common chimpanzee, rhesus macaque, cattle, dog, mouse, rat, tropical clawed frog, and zebra fish.
References
Text derived from https://en.wikipedia.org/w/index.php?oldid=1319570299 under CC BY-SA 4.0; modifications have been made.