Lesson plan
Complement component 1r
Complement C1r subcomponent ( , activated complement C1r, C overbar 1r esterase, C1r) is a protein involved in the complement system of the innate immune system. In humans, C1r is encoded by the C1R gene. C1r along with C1q and C1s form the C1 complex, which is the first component of the serum complement system. C1r is an enzyme that activates C1s to its active form, by proteolytic cleavage.
Article summary
Complement C1r subcomponent ( , activated complement C1r, C overbar 1r esterase, C1r) is a protein involved in the complement system of the innate immune system. In humans, C1r is encoded by the C1R gene. C1r along with C1q and C1s form the C1 complex, which is the first component of the serum complement system. C1r is an enzyme that activates C1s to its active form, by proteolytic cleavage.
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Discussion questions
- Summarise the article in your own words. Which single claim would you verify first, and why?
- Which claim in this article is most likely to be revised as the sources update? How would you check its current status?
- If two sources disagreed about one of these facts, what would you need in order to trust one over the other?
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