Lesson plan
Complement component 3
Complement component 3, often simply called C3, is a protein of the immune system that is found primarily in the blood. It plays a central role in the complement system of vertebrate animals and contributes to innate immunity. In humans, it is encoded on chromosome 19 by a gene called C3. Deficiencies and defects of C3 result in the affected person being immunocompromised and particularly vulnerable to bacterial infections.
Article summary
Complement component 3, often simply called C3, is a protein of the immune system that is found primarily in the blood. It plays a central role in the complement system of vertebrate animals and contributes to innate immunity. In humans, it is encoded on chromosome 19 by a gene called C3. Deficiencies and defects of C3 result in the affected person being immunocompromised and particularly vulnerable to bacterial infections.
Key claims
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Discussion questions
- Summarise the article in your own words. Which single claim would you verify first, and why?
- Which claim in this article is most likely to be revised as the sources update? How would you check its current status?
- If two sources disagreed about one of these facts, what would you need in order to trust one over the other?
Bibliography
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Key claims and bibliography are generated from the same tracked claims and sources as the article page.