Lesson plan
Craig plot
The Craig plot, named after Paul N. Craig, is a plot of two substituent parameters (e.g. Hansch-Fujita π constant and sigma constant) used in rational drug design. Two most used forms of a Craig plot are * plotting the sigma constants of the Hammett equation versus hydrophobicity * plotting the steric terms of the Taft equation against hydrophobicity
Article summary
The Craig plot, named after Paul N. Craig, is a plot of two substituent parameters (e.g. Hansch-Fujita π constant and sigma constant) used in rational drug design. Two most used forms of a Craig plot are * plotting the sigma constants of the Hammett equation versus hydrophobicity * plotting the steric terms of the Taft equation against hydrophobicity
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Discussion questions
- Summarise the article in your own words. Which single claim would you verify first, and why?
- Which claim in this article is most likely to be revised as the sources update? How would you check its current status?
- If two sources disagreed about one of these facts, what would you need in order to trust one over the other?
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Key claims and bibliography are generated from the same tracked claims and sources as the article page.