Lesson plan

DbSNP

The Single Nucleotide Polymorphism Database (dbSNP) is a free public archive for genetic variation within and across different species developed and hosted by the National Center for Biotechnology Information (NCBI) in collaboration with the National Human Genome Research Institute (NHGRI). Although the name of the database implies a collection of only single nucleotide polymorphisms (SNPs), it in fact contains a range of molecular variation: SNPs, short deletion and insertion polymorphisms (indels), microsatellite markers or short tandem repeats (STRs), multinucleotide polymorphisms (MNPs), heterozygous sequences, and named variants. The dbSNP accepts apparently neutral polymorphisms, polymorphisms corresponding to known phenotypes, and regions of no variation. It was created in September 1998 to supplement GenBank, NCBI's collection of publicly available nucleic acid and protein sequences. In 2017, NCBI stopped support for all non-human organisms in dbSNP. As of build 153 (released in August 2019), dbSNP had amassed nearly 2 billion submissions representing more than 675 million distinct variants for Homo sapiens.

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Article summary

The Single Nucleotide Polymorphism Database (dbSNP) is a free public archive for genetic variation within and across different species developed and hosted by the National Center for Biotechnology Information (NCBI) in collaboration with the National Human Genome Research Institute (NHGRI). Although the name of the database implies a collection of only single nucleotide polymorphisms (SNPs), it in fact contains a range of molecular variation: SNPs, short deletion and insertion polymorphisms (indels), microsatellite markers or short tandem repeats (STRs), multinucleotide polymorphisms (MNPs), heterozygous sequences, and named variants. The dbSNP accepts apparently neutral polymorphisms, polymorphisms corresponding to known phenotypes, and regions of no variation. It was created in September 1998 to supplement GenBank, NCBI's collection of publicly available nucleic acid and protein sequences. In 2017, NCBI stopped support for all non-human organisms in dbSNP. As of build 153 (released in August 2019), dbSNP had amassed nearly 2 billion submissions representing more than 675 million distinct variants for Homo sapiens.

Key claims

  1. release date: 2019 — source: Wikipedia · confidence 0.95

Discussion questions

  1. Summarise the article in your own words. Which single claim would you verify first, and why?
  2. The record states that the release date is "2019". What evidence would count against this claim?
  3. Which claim in this article is most likely to be revised as the sources update? How would you check its current status?
  4. If two sources disagreed about one of these facts, what would you need in order to trust one over the other?

Bibliography

  1. Wikipedia https://en.wikipedia.org/w/index.php?oldid=1359588711

Key claims and bibliography are generated from the same tracked claims and sources as the article page.