Lesson plan

Dc1a

Dc1a (β-diguetoxin or DTX9.2) is a potent insect-selective poisonous 57-residue peptide that is produced by the desert bush spider (Diguetia canities). It promotes the opening of voltage-gated Na channels (Na v ) in German cockroach German cockroach (Blattella germanica) by interacting with the paddle motif in domain II.

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Article summary

Dc1a (β-diguetoxin or DTX9.2) is a potent insect-selective poisonous 57-residue peptide that is produced by the desert bush spider (Diguetia canities). It promotes the opening of voltage-gated Na channels (Na v ) in German cockroach German cockroach (Blattella germanica) by interacting with the paddle motif in domain II.

Key claims

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Discussion questions

  1. Summarise the article in your own words. Which single claim would you verify first, and why?
  2. Which claim in this article is most likely to be revised as the sources update? How would you check its current status?
  3. If two sources disagreed about one of these facts, what would you need in order to trust one over the other?

Bibliography

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Key claims and bibliography are generated from the same tracked claims and sources as the article page.