Diberal
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Diberal, also known as 5-(1,3-Dimethylbutyl)-5-ethylbarbituric acid or DMBB, is an atypical barbiturate. This compound can be either convulsant or anticonvulsant depending on which enantiomer is used.
Diberal, also known as 5-(1,3-Dimethylbutyl)-5-ethylbarbituric acid or DMBB, is an atypical barbiturate. This compound can be either convulsant or anticonvulsant depending on which enantiomer is used. ==Pharmacology== Diberal, unlike most barbiturates, can have convulsant actions. This is uncommon, as barbiturates typically enhance the function of GABA as allorestic modulators and agonists (at higher doses), therefore having anticonvulsant properties. Depending on which isomer is used, it can have either convulsant or anticonvulsant actions. The different pharmacological profile between isomers is thought to be due to the differences in the formation of hydrogen bonds at the binding sites. ==See also== CHEB McN-481
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