Lesson plan
Dio1
Type I iodothyronine deiodinase is an enzyme that in humans is encoded by the DIO1 gene. This enzyme is a type of iodothyronine deiodinase ( / ), which are enzymes involved in activating and deactivate thyroid hormones by removing iodine atoms from them (called deiodination). This form is distinct in being capable of both activation and inactivation, unlike type II iodothyronine deiodinase which can only activate ( ) thyroid hormones, and type III iodothyronine deiodinase which can only deactivate ( ) thyroid hormones.
Article summary
Type I iodothyronine deiodinase is an enzyme that in humans is encoded by the DIO1 gene. This enzyme is a type of iodothyronine deiodinase ( / ), which are enzymes involved in activating and deactivate thyroid hormones by removing iodine atoms from them (called deiodination). This form is distinct in being capable of both activation and inactivation, unlike type II iodothyronine deiodinase which can only activate ( ) thyroid hormones, and type III iodothyronine deiodinase which can only deactivate ( ) thyroid hormones.
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Discussion questions
- Summarise the article in your own words. Which single claim would you verify first, and why?
- Which claim in this article is most likely to be revised as the sources update? How would you check its current status?
- If two sources disagreed about one of these facts, what would you need in order to trust one over the other?
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