DNAJC19
≈ 1 min read
Names in other languages
- DeutschDNAJC19
- EnglishDNAJC19
- EspañolDNAJC19
- FrançaisDNAJC19
- ItalianoDNAJC19
- NederlandsDNAJC19
- PortuguêsDNAJC19
- srnDNAJC19
Article bodies are English and are not machine-translated. A name in another language is not a translation of the article.
Mitochondrial import inner membrane translocase subunit TIM14 is an enzyme that in humans is encoded by the DNAJC19 gene on chromosome 3. TIM14 belongs to the DnaJ family, which has been involved in Hsp40/Hsp70 chaperone systems. As a mitochondrial chaperone, TIM14 functions as part of the TIM23 complex import motor to facilitate the import of nuclear-encoded proteins into the mitochondria. TIM14 also complexes with prohibitin complexes to regulate mitochondrial morphogenesis, and has been implicated in dilated cardiomyopathy with ataxia.
Mitochondrial import inner membrane translocase subunit TIM14 is an enzyme that in humans is encoded by the DNAJC19 gene on chromosome 3. TIM14 belongs to the DnaJ family, which has been involved in Hsp40/Hsp70 chaperone systems. As a mitochondrial chaperone, TIM14 functions as part of the TIM23 complex import motor to facilitate the import of nuclear-encoded proteins into the mitochondria. TIM14 also complexes with prohibitin complexes to regulate mitochondrial morphogenesis, and has been implicated in dilated cardiomyopathy with ataxia.
Text derived from https://en.wikipedia.org/w/index.php?oldid=1374770529 under CC BY-SA 4.0; modifications have been made.