DOx

(2,5-DMA), the base chemical structure of the DOx family. 4-Substituted-2,5-dimethoxyamphetamines (DOx) is a chemical class of substituted amphetamine derivatives featuring methoxy groups at the 2- and 5- positions of the phenyl ring, and a substituent such as alkyl or halogen at the 4- position of the phenyl ring. They are 4-substituted derivatives of 2,5-dimethoxyamphetamine (2,5-DMA, DOH) and are structurally related to the naturally occurring phenethylamine psychedelic mescaline. The most well-known DOx drugs are DOM, DOI, DOB, DOET, and DOC. DOI is widely used in scientific research. DOM has been used as a recreational drug, while DOET was an experimental pharmaceutical drug. Most compounds of this class are potent and long-lasting psychedelic drugs, and act as selective 5-HT 2A , 5-HT 2B , and 5-HT 2C receptor agonists. A few bulkier derivatives such as DOAM have similarly high affinity for 5-HT 2 receptors but have reduced efficacy and potency as psychedelics. DOI has been found to have extraordinarily potent anti-inflammatory effects. These properties are not shared by all other related drugs and appear to be mediated by functionally selective serotonin 5-HT 2A receptor activation. The anti-inflammatory effects of DOI and related drugs may have medical applications.

Dox or DOX may refer to: ==Chemistry== Desferrioxamine, a chelating agent used to remove excess iron from the body Dissolved oxygen, a relative measure of the amount of oxygen that is dissolved or carried in a given medium Doxorubicin, an anthracycline antibiotic used in cancer therapy DOx, 2,5-dimethoxy, 4-substituted amphetamines Doxycycline, a semi-synthetic tetracycline Sodium dithionite (D-Ox) ==People== Dox (poet), born Jean Verdi Salomon Razakandrainy (1913¹–1978), a significant poet from Madagascar Dox Hendrix (born 1959), U.S. pro-wrestler Dox Thrash (1893–1965), African-American artist ===People with the surname=== Arthur Wayland Dox, a biologist who popularized Czapek-Dox medium Gerrit L. Dox (1784–1847), American politician, New York State Treasurer Myndert M. Dox (1790–1830), American soldier and government official Peter Myndert Dox (1813–1891), American politician Virginia Dox (1851–1941), American missionary, educator, and explorer ===Characters=== Vril Dox, a DC Comics character Querl Dox, a DC Comics character General Dox, a character in the Marvel Cinematic Universe King Dox of Foxville, a character from the 1909 L. Frank Baum book The Road to Oz ==Places== Dox, a white dwarf star named SDSS J1240+6710 which contains a nearly pure oxygen atmosphere Dox Formation, a Mesoproterozoic sandstone formation outcrop in the Grand Canyon Dox Castle, a summit in the Grand Canyon DOX Centre for Contemporary Art, Holešovice, Prague, Czechia ==Other uses== Bussa language (ISO 639 language code dox ), a language found in Ethiopia Dox, a type of Warez Dornier Do X, the German aircraft Direct oximetry Canid hybrid, a supposed hybrid between a fox and a dog Doxing, researching and publishing personally identifiable information about an individual without their consent Design of experiments, a statistical approach to experimental design ==See also== Dock (disambiguation) Doc (disambiguation) Docs (disambiguation) Documentation (disambiguation)

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