Esterom
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Esterom is an investigational drug that was studied for use as a topical analgesic. Chemically, it is a mixture of compounds derived from the esterification of cocaine in propylene glycol. While the major component is benzoylecgonine, the analgesic activity is likely due to hydroxypropyl benzoylecgonine, the only component that penetrates the skin. Clinical trials of Esterom failed so show a statistically significant benefit for patients in 2002 and was never approved.
Esterom is an investigational drug that was studied for use as a topical analgesic. Chemically, it is a mixture of compounds derived from the esterification of cocaine in propylene glycol. While the major component is benzoylecgonine, the analgesic activity is likely due to hydroxypropyl benzoylecgonine, the only component that penetrates the skin. Clinical trials of Esterom failed so show a statistically significant benefit for patients in 2002 and was never approved.
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