Estrone

Article summary

Estrone (E1), also spelled oestrone, is a steroid, a weak estrogen, and a minor female sex hormone. It is one of three major endogenous estrogens, the others being estradiol and estriol. Estrone, as well as the other estrogens, are synthesized from cholesterol and secreted mainly from the gonads, though they can also be formed from adrenal androgens in adipose tissue. Relative to estradiol, both estrone and estriol have far weaker activity as estrogens. Estrone can be converted into estradiol, and serves mainly as a precursor or metabolic intermediate of estradiol. It is both a precursor and metabolite of estradiol. In addition to its role as a natural hormone, estrone has been used as a medication, for instance in menopausal hormone therapy; for information on estrone as a medication, see the estrone (medication) article.

Key claims

1. date of establishment: 1932 — source: Wikipedia · confidence 0.95

Discussion questions

1. Summarise the article in your own words. Which single claim would you verify first, and why?
2. The record states that the date of establishment is "1932". What evidence would count against this claim?
3. Which claim in this article is most likely to be revised as the sources update? How would you check its current status?
4. If two sources disagreed about one of these facts, what would you need in order to trust one over the other?

Bibliography

1. Wikipedia https://en.wikipedia.org/w/index.php?oldid=1365575615