Lesson plan

FEZ2

Fasciculation and elongation protein zeta-2 is a protein that in humans is encoded by the FEZ2 gene. This gene is an ortholog of the C. elegans unc-76 gene, which is necessary for normal axonal bundling and elongation within axon bundles. Other orthologs include the rat gene that encodes II, which can bind to synaptotagmin.

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Article summary

Fasciculation and elongation protein zeta-2 is a protein that in humans is encoded by the FEZ2 gene. This gene is an ortholog of the C. elegans unc-76 gene, which is necessary for normal axonal bundling and elongation within axon bundles. Other orthologs include the rat gene that encodes II, which can bind to synaptotagmin.

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  1. Summarise the article in your own words. Which single claim would you verify first, and why?
  2. Which claim in this article is most likely to be revised as the sources update? How would you check its current status?
  3. If two sources disagreed about one of these facts, what would you need in order to trust one over the other?

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