HUS1
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Checkpoint protein HUS1 is a protein that in humans is encoded by the HUS1 gene.
Checkpoint protein HUS1 is a protein that in humans is encoded by the HUS1 gene.
In somatic cells
In somatic cells the RAD9-RAD1-HUS1 (9-1-1) complex responds to DNA damage by promoting DNA repair.
In meiosis
In flies, worms and yeast, the 9-1-1 complex is necessary for meiotic checkpoint function and efficient meiotic recombination. During mammalian meiosis 9-1-1 complexes promote synapsis of homologous chromosomes, double-strand break repair and cell cycle checkpoint signalling.
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