Lesson plan
Hydroamination
In organic chemistry, hydroamination is the formal addition of an bond of an amine across a carbon-carbon multiple bond of an alkene, alkyne, diene, or allene. In the ideal case, hydroamination is atom economical and green; and the products could see extensive use in fine-chemical, pharmaceutical, and agricultural industries. Hydroamination reactions occur spontaneously only for electrophilic alkenes and some dienes, but these are known by other names (e.g. Michael addition reaction); "hydroamination" is generally reserved for situations where the reaction requires a catalyst. Hydroamination is however of little value industrially. Hydroamination can be used intramolecularly to create heterocycles or intermolecularly with a separate amine and unsaturated compound. File:Examples of intermolecular hydroamination.png|alt=Prototypical intermolecular hydroamination reactions.|Prototypical intermolecular hydroamination reactions. File:Examples of intramolecular hydroamination (2).png|alt=Examples of intramolecular hydroamination.|Examples of intramolecular hydroamination.
Article summary
In organic chemistry, hydroamination is the formal addition of an bond of an amine across a carbon-carbon multiple bond of an alkene, alkyne, diene, or allene. In the ideal case, hydroamination is atom economical and green; and the products could see extensive use in fine-chemical, pharmaceutical, and agricultural industries. Hydroamination reactions occur spontaneously only for electrophilic alkenes and some dienes, but these are known by other names (e.g. Michael addition reaction); "hydroamination" is generally reserved for situations where the reaction requires a catalyst. Hydroamination is however of little value industrially. Hydroamination can be used intramolecularly to create heterocycles or intermolecularly with a separate amine and unsaturated compound. File:Examples of intermolecular hydroamination.png|alt=Prototypical intermolecular hydroamination reactions.|Prototypical intermolecular hydroamination reactions. File:Examples of intramolecular hydroamination (2).png|alt=Examples of intramolecular hydroamination.|Examples of intramolecular hydroamination.
Key claims
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Discussion questions
- Summarise the article in your own words. Which single claim would you verify first, and why?
- Which claim in this article is most likely to be revised as the sources update? How would you check its current status?
- If two sources disagreed about one of these facts, what would you need in order to trust one over the other?
Bibliography
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Key claims and bibliography are generated from the same tracked claims and sources as the article page.