IBMX
≈ 1 min read
Names in other languages
No names in other languages are held for this entry yet.
Article bodies are English and are not machine-translated. A name in another language is not a translation of the article.
IBMX (3-isobutyl-1-methylxanthine), like other methylxanthine derivatives, is both a: # competitive non-selective phosphodiesterase inhibitor which raises intracellular cAMP, activates PKA, inhibits TNFα and leukotriene synthesis, and reduces inflammation and innate immunity, and # nonselective adenosine receptor antagonist. As a phosphodiesterase inhibitor, IBMX has IC 50 = 2–50 μM and does not inhibit PDE8 or PDE9.
IBMX (3-isobutyl-1-methylxanthine), like other methylxanthine derivatives, is both a: competitive non-selective phosphodiesterase inhibitor which raises intracellular cAMP, activates PKA, inhibits TNFα and leukotriene synthesis, and reduces inflammation and innate immunity, and nonselective adenosine receptor antagonist. As a phosphodiesterase inhibitor, IBMX has IC 50 = 2–50 μM and does not inhibit PDE8 or PDE9. ==References==
Text derived from https://en.wikipedia.org/w/index.php?oldid=1371048277 under CC BY-SA 4.0; modifications have been made.