Lesson plan

Idose

Idose is a hexose, a six carbon monosaccharide. It has an aldehyde group and is thus an aldose. Idose is not found in nature, but its oxidized derivative iduronic acid, is a component of dermatan sulfate and heparan sulfate, which are glycosaminoglycans. The first and third hydroxyls point the opposite way from the second and fourth. It is made by aldol condensation of D - and L -glyceraldehyde. L -Idose is a C-5 epimer of D -glucose. It can be identified by mass spectrometry.

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Article summary

Idose is a hexose, a six carbon monosaccharide. It has an aldehyde group and is thus an aldose. Idose is not found in nature, but its oxidized derivative iduronic acid, is a component of dermatan sulfate and heparan sulfate, which are glycosaminoglycans. The first and third hydroxyls point the opposite way from the second and fourth. It is made by aldol condensation of D - and L -glyceraldehyde. L -Idose is a C-5 epimer of D -glucose. It can be identified by mass spectrometry.

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  1. Summarise the article in your own words. Which single claim would you verify first, and why?
  2. Which claim in this article is most likely to be revised as the sources update? How would you check its current status?
  3. If two sources disagreed about one of these facts, what would you need in order to trust one over the other?

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