Lesson plan
ISLR
In humans, the immunoglobulin super family containing leucine-rich repeat (ISLR) protein is encoded by the ISLR gene. Current RNA-seq studies show that the protein is highly expressed in the endometrium and ovary and shows expression among 25 other tissues. The protein is seen localized in the cytoplasm, plasma membrane, extracellular exosome, and platelet alpha granule lumen. Furthermore, the protein is known to play a role in platelet degranulation, cell adhesion, and response to elevated platelet cytosolic Ca 2+ .
Article summary
In humans, the immunoglobulin super family containing leucine-rich repeat (ISLR) protein is encoded by the ISLR gene. Current RNA-seq studies show that the protein is highly expressed in the endometrium and ovary and shows expression among 25 other tissues. The protein is seen localized in the cytoplasm, plasma membrane, extracellular exosome, and platelet alpha granule lumen. Furthermore, the protein is known to play a role in platelet degranulation, cell adhesion, and response to elevated platelet cytosolic Ca 2+ .
Key claims
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Discussion questions
- Summarise the article in your own words. Which single claim would you verify first, and why?
- Which claim in this article is most likely to be revised as the sources update? How would you check its current status?
- If two sources disagreed about one of these facts, what would you need in order to trust one over the other?
Bibliography
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Key claims and bibliography are generated from the same tracked claims and sources as the article page.