Lesson plan
KANK2
KN motif and ankyrin repeat domain-containing protein 2 is a protein that in humans is encoded by the KANK2 gene (previously ANKRD25). KANK2 has various regulatory functions, including regulating nuclear receptor coactivators (eg: NCOA1, NCOA2, and NCOA3), sequestering the apoptosis signaling protein AIFM1, inhibiting vitamin D signaling, interacting with ARHGDIA to regulate the formation of actin stress fibers, and regulating rho signaling.
Article summary
KN motif and ankyrin repeat domain-containing protein 2 is a protein that in humans is encoded by the KANK2 gene (previously ANKRD25). KANK2 has various regulatory functions, including regulating nuclear receptor coactivators (eg: NCOA1, NCOA2, and NCOA3), sequestering the apoptosis signaling protein AIFM1, inhibiting vitamin D signaling, interacting with ARHGDIA to regulate the formation of actin stress fibers, and regulating rho signaling.
Key claims
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Discussion questions
- Summarise the article in your own words. Which single claim would you verify first, and why?
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- If two sources disagreed about one of these facts, what would you need in order to trust one over the other?
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