LMO1

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Rhombotin-1 is a protein that in humans is encoded by the LMO1 gene. LMO1 encodes a cysteine-rich, two LIM domain transcriptional regulator. It is mapped to an area of consistent chromosomal translocation in chromosome 11, disrupting it in T-cell leukemia, although more rarely than the related gene, LMO2 is disrupted.

Rhombotin-1 is a protein that in humans is encoded by the LMO1 gene. LMO1 encodes a cysteine-rich, two LIM domain transcriptional regulator. It is mapped to an area of consistent chromosomal translocation in chromosome 11, disrupting it in T-cell leukemia, although more rarely than the related gene, LMO2 is disrupted.

Interactions

LMO1 has been shown to interact with GATA3 and TAL1.

References

Further reading

Text derived from https://en.wikipedia.org/w/index.php?oldid=1301017269 under CC BY-SA 4.0; modifications have been made.

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