Lesson plan
MARCH2
E3 ubiquitin-protein ligase MARCHF2 is an enzyme that in humans is encoded by the MARCHF2 gene (previously MARCH2). It is a member of the MARCH family of E3 ligases, and plays an important role in the turnover of membrane proteins. MARCH2 has been shown to negatively regulate NF-κB essential modulator function upon viral and bacterial infections.
Article summary
E3 ubiquitin-protein ligase MARCHF2 is an enzyme that in humans is encoded by the MARCHF2 gene (previously MARCH2). It is a member of the MARCH family of E3 ligases, and plays an important role in the turnover of membrane proteins. MARCH2 has been shown to negatively regulate NF-κB essential modulator function upon viral and bacterial infections.
Key claims
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Discussion questions
- Summarise the article in your own words. Which single claim would you verify first, and why?
- Which claim in this article is most likely to be revised as the sources update? How would you check its current status?
- If two sources disagreed about one of these facts, what would you need in order to trust one over the other?
Bibliography
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Key claims and bibliography are generated from the same tracked claims and sources as the article page.