Lesson plan

Microbial pathogenesis

Microbial pathogenesis is a field of microbiology that started at least as early as 1988, with the identification of the triune Falkow's criteria, molecular Koch's postulates. In 1996, Fredricks and Relman proposed a seven-point list of "Molecular Guidelines for Establishing Microbial Disease Causation," because of "the discovery of nucleic acids" by Watson and Crick "as the source of genetic information and as the basis for precise characterization of an organism." The subsequent development of the "ability to detect and manipulate these nucleic acid molecules in microorganisms has created a powerful means for identifying previously unknown microbial pathogens and for studying the host-parasite relationship." __TOC__

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Article summary

Microbial pathogenesis is a field of microbiology that started at least as early as 1988, with the identification of the triune Falkow's criteria, molecular Koch's postulates. In 1996, Fredricks and Relman proposed a seven-point list of "Molecular Guidelines for Establishing Microbial Disease Causation," because of "the discovery of nucleic acids" by Watson and Crick "as the source of genetic information and as the basis for precise characterization of an organism." The subsequent development of the "ability to detect and manipulate these nucleic acid molecules in microorganisms has created a powerful means for identifying previously unknown microbial pathogens and for studying the host-parasite relationship." __TOC__

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Discussion questions

  1. Summarise the article in your own words. Which single claim would you verify first, and why?
  2. Which claim in this article is most likely to be revised as the sources update? How would you check its current status?
  3. If two sources disagreed about one of these facts, what would you need in order to trust one over the other?

Bibliography

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Key claims and bibliography are generated from the same tracked claims and sources as the article page.