MPEG-G
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MPEG-G (ISO / IEC 23092) is an ISO/IEC standard designed for genomic information representation by the collaboration of the ISO/IEC JTC 1/SC 29/WG 9 (MPEG) and ISO TC 276 "Biotechnology" Work Group 5. The goal of the standard is to provide interoperable solutions for data storage, access, and protection across different possible implementations for data information generated by high-throughput sequencing machines and their subsequent processing and analysis. The standard is composed of different parts, each one addressing a specific aspect, such as compression, metadata association, Application Programming Interfaces (APIs), and a reference software for data decoding. Together with the reference decoder software, commercial and open source implementations started to be available in 2019, covering progressively more of the published parts of the standard.
MPEG-G (ISO / IEC 23092) is an ISO/IEC standard designed for genomic information representation by the collaboration of the ISO/IEC JTC 1/SC 29/WG 9 (MPEG) and ISO TC 276 "Biotechnology" Work Group 5. The goal of the standard is to provide interoperable solutions for data storage, access, and protection across different possible implementations for data information generated by high-throughput sequencing machines and their subsequent processing and analysis. The standard is composed of different parts, each one addressing a specific aspect, such as compression, metadata association, Application Programming Interfaces (APIs), and a reference software for data decoding. Together with the reference decoder software, commercial and open source implementations started to be available in 2019, covering progressively more of the published parts of the standard.
Background
The advent of high-throughput sequencing (HTS) technologies has revolutionized the field of quantitative biology. Availability of large collections of genomic information has now entered everyday practice and has become a cornerstone of a number of disciplines, ranging from biological research to personalized medicine in the clinic. At the moment, genomic information is mostly exchanged through a variety of data formats, such as FASTA/FASTQ for unaligned sequencing reads and SAM/BAM/CRAM for aligned reads. The ISO/IEC 23092 (MPEG-G) standard aims to provide a unified format for the efficient representation and compression of such diverse data, both for file storage and data transport. In order to do that, the standard is divided in several parts.
See also
MPEG ISO/IEC JTC 1/SC 29
References
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