MSRB1
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Methionine-R-sulfoxide reductase B1 is an enzyme that in humans is encoded by the MSRB1 gene. This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. This protein belongs to the methionine sulfoxide reductase B (MsrB) family, and it is expressed in a variety of adult and fetal tissues.
Methionine-R-sulfoxide reductase B1 is an enzyme that in humans is encoded by the MSRB1 gene. This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. This protein belongs to the methionine sulfoxide reductase B (MsrB) family, and it is expressed in a variety of adult and fetal tissues.
See also
MSRA (gene) MSRB2 Methionine oxidation
References
Further reading
Text derived from https://en.wikipedia.org/w/index.php?oldid=1378731783 under CC BY-SA 4.0; modifications have been made.