Oogenesis

Article summary

Oogenesis ( ) or ovogenesis is female gametogenesis, the development of the egg cell (ovum) from the oogonium to a primary oocyte, and secondary oocyte. The egg cell is a cell that is competent to further develop when fertilized. Oogenesis is initiated during early embryonic development. Oogonia originate from primordial germ cells (PGCs). The primordial germ cells arise from extraembryonic tissue, known as fetal membranes in humans and other mammals. Somatic cells arise from embryonic tissue. In the extraembryonic tissues the primordial germ cells avoid differentiation signals. PGCs migrate to the genital ridges, precursors to the gonads, ovaries in females, where they proliferate by mitosis to produce a large number of oogonia as primary oocytes.

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