PAK2

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Serine/threonine-protein kinase PAK 2 is an enzyme that in humans is encoded by the PAK2 gene. PAK2 is one of three members of Group I PAK family of serine/threonine kinases. The PAKs are evolutionary conserved. PAK2 and its cleaved fragment localize in both the cytoplasmic or nuclear compartments. PAK2 signaling modulates apoptosis, endothelial lumen formation, viral pathogenesis, and cancer including, breast, hepatocarcinoma, gastric and cancer, at-large, and, based on its kinase activity alone, peripheral nerve myelination during embryonic development.

Serine/threonine-protein kinase PAK 2 is an enzyme that in humans is encoded by the PAK2 gene. PAK2 is one of three members of Group I PAK family of serine/threonine kinases. The PAKs are evolutionary conserved. PAK2 and its cleaved fragment localize in both the cytoplasmic or nuclear compartments. PAK2 signaling modulates apoptosis, endothelial lumen formation, viral pathogenesis, and cancer including, breast, hepatocarcinoma, gastric and cancer, at-large, and, based on its kinase activity alone, peripheral nerve myelination during embryonic development. ==Notes== PAK2 Info with links in the Cell Migration Gateway

Text derived from https://en.wikipedia.org/w/index.php?oldid=1310974223 under CC BY-SA 4.0; modifications have been made.