Parm

ParM is a prokaryotic actin homologue which provides the force to drive copies of the R1 plasmid to opposite ends of rod shaped bacteria before cytokinesis. ParM is a monomer that is encoded in the DNA of the R1 plasmid and manufactured by the host cell's ribosomes. In the cytoplasm it spontaneously polymerizes forming short strands that either bind to ParR or hydrolyze. ParR stabilizes ParM and prevents it from hydrolyzing. Once bound by ParR at both ends, monomer units continue to attach to the ends of the ParM and the resulting reaction pushes R1 plasmids to opposite ends of the cell. ParMs from different bacterial plasmids can form astonishingly diverse helical structures comprising two or four strands to maintain faithful plasmid inheritance.

Parm or PARM may refer to: Parmesan cheese, especially in dishes such as chicken parm PARM 1 mine, Panzer-Abwehr Richtmine (German, Antitank defense arranging mine) Authentic Party of the Mexican Revolution, Partido Auténtico de la Revolución Mexicana (Spanish) ParM, a component of the segregation mechanism for the bacterial R1 plasmid parm AG, a Swiss software and consulting company Persistent Anti-Radiation Missile, an acronym commonly associated with the AGM-136A Tacit Rainbow cruise missile

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