Lesson plan

Pleuran

Pleuran is an insoluble polysaccharide (β-(1,3/1,6)-D-glucan), isolated from Pleurotus ostreatus. Pleuran belongs to a group of glucose polymers commonly called beta-glucans demonstrating biological response modifier properties. These immunomodulating properties render the host more resistant to infections and neoplasms. In a study published in December 2010, pleuran demonstrated to have a protective effect against exercise-induced suppression of immune cell activity (NK cells) in subjects taking 100 mg per day. In another study published in 2011, pleuran reduced the incidence of upper respiratory tract infections and increased the number of circulating NK cells. Pleuran is also being studied as a potential immunologic adjuvant.

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Article summary

Pleuran is an insoluble polysaccharide (β-(1,3/1,6)-D-glucan), isolated from Pleurotus ostreatus. Pleuran belongs to a group of glucose polymers commonly called beta-glucans demonstrating biological response modifier properties. These immunomodulating properties render the host more resistant to infections and neoplasms. In a study published in December 2010, pleuran demonstrated to have a protective effect against exercise-induced suppression of immune cell activity (NK cells) in subjects taking 100 mg per day. In another study published in 2011, pleuran reduced the incidence of upper respiratory tract infections and increased the number of circulating NK cells. Pleuran is also being studied as a potential immunologic adjuvant.

Key claims

  1. publication date: 2010 — source: Wikipedia · confidence 0.95
  2. publication date: 2011 — source: Wikipedia · confidence 0.95

Discussion questions

  1. Summarise the article in your own words. Which single claim would you verify first, and why?
  2. The record states that the publication date is "2010". What evidence would count against this claim?
  3. The record states that the publication date is "2011". What evidence would count against this claim?
  4. Which claim in this article is most likely to be revised as the sources update? How would you check its current status?
  5. If two sources disagreed about one of these facts, what would you need in order to trust one over the other?

Bibliography

  1. Wikipedia https://en.wikipedia.org/w/index.php?oldid=1304267599

Key claims and bibliography are generated from the same tracked claims and sources as the article page.