Lesson plan

Polyphenon

Polyphenon is a series of high grade green tea polyphenol extracts manufactured by the Mitsui Norin Co., Ltd. of Japan. The extracts are in part the result of a water based extraction method which begins with green tea leaves, and then involves successive steps which concentrate the catechins thought to be responsible for the health benefits of green tea. As of October 2016, 20 clinical trials have been published for Polyphenon E (16 oral and 4 topical). In 2006 the U.S. Food and Drug Administration approved as a drug an ointment containing 15% Polyphenon E for the treatment of genital and perianal warts. The product name is Veregen. To date, no oral use of the product has been approved. Many dietary supplement companies sell green tea extracts as supplements, but as such, are not allowed to make any disease treatment or prevention claims.

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Article summary

Polyphenon is a series of high grade green tea polyphenol extracts manufactured by the Mitsui Norin Co., Ltd. of Japan. The extracts are in part the result of a water based extraction method which begins with green tea leaves, and then involves successive steps which concentrate the catechins thought to be responsible for the health benefits of green tea. As of October 2016, 20 clinical trials have been published for Polyphenon E (16 oral and 4 topical). In 2006 the U.S. Food and Drug Administration approved as a drug an ointment containing 15% Polyphenon E for the treatment of genital and perianal warts. The product name is Veregen. To date, no oral use of the product has been approved. Many dietary supplement companies sell green tea extracts as supplements, but as such, are not allowed to make any disease treatment or prevention claims.

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  1. Summarise the article in your own words. Which single claim would you verify first, and why?
  2. Which claim in this article is most likely to be revised as the sources update? How would you check its current status?
  3. If two sources disagreed about one of these facts, what would you need in order to trust one over the other?

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