Primary bone
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Primary bone is the first bone tissue that appears in embryonic development and in fracture repair. It is characterized by its random position of collagen fibers. In most places in adults this tissue is replaced by secondary bone tissue except, for example, near the sutures of calvara or tooth sockets. The secondary bones have lower amounts of osteocytes so primary bone is much more easily penetrated by x-ray.
Primary bone is the first bone tissue that appears in embryonic development and in fracture repair. It is characterized by its random position of collagen fibers. In most places in adults this tissue is replaced by secondary bone tissue except, for example, near the sutures of calvara or tooth sockets. The secondary bones have lower amounts of osteocytes so primary bone is much more easily penetrated by x-ray. ==Clinical significance== Primary bone or the primary ossification center is the beginning of the bone building process during the first trimester. Calcificed cartilage is basophilic and new bone being made is more acidophilic. The primary ossification occurs in the diaphysis. In contrast, secondary ossification centers appear later at the epiphyses of the cartilage and develop similarly to the diaphysis. ==See also== Somite Somitogenesis ==References==
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