Lesson plan
Proctolin
Proctolin is a neuropeptide present in insects and crustaceans. It was first found in Periplaneta americana, a species of cockroach in 1975. Proctolin was extracted from 125,000 cockroaches and the Edman degradation was carried out on the sample to determine the amino acid sequence, which is Arg-Tyr-Leu-Pro-Thr. Proctolin was the first insect neuropeptide to be sequenced. Starratt and Brown identified it as a visceral muscle neurotransmitter. However, it now appears that there are many more functions of proctolin, and it is present in many more species.
Article summary
Proctolin is a neuropeptide present in insects and crustaceans. It was first found in Periplaneta americana, a species of cockroach in 1975. Proctolin was extracted from 125,000 cockroaches and the Edman degradation was carried out on the sample to determine the amino acid sequence, which is Arg-Tyr-Leu-Pro-Thr. Proctolin was the first insect neuropeptide to be sequenced. Starratt and Brown identified it as a visceral muscle neurotransmitter. However, it now appears that there are many more functions of proctolin, and it is present in many more species.
Key claims
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Discussion questions
- Summarise the article in your own words. Which single claim would you verify first, and why?
- Which claim in this article is most likely to be revised as the sources update? How would you check its current status?
- If two sources disagreed about one of these facts, what would you need in order to trust one over the other?
Bibliography
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Key claims and bibliography are generated from the same tracked claims and sources as the article page.