Lesson plan
SERCA
SERCA (sarcoplasmic/endoplasmic reticulum Ca 2+ -ATPase or SR Ca 2+ -ATPase) is a membrane protein that transports calcium from the cytosol into the sarcoplasmic reticulum (SR) of muscle cells. The SR is a structure which stores calcium in muscle cells, similar to the smooth endoplasmic reticulum of other cells. SERCA is a calcium ATPase-type P-ATPase. It uses energy from ATP to actively transport calcium ions across the SR membrane.
Article summary
SERCA (sarcoplasmic/endoplasmic reticulum Ca 2+ -ATPase or SR Ca 2+ -ATPase) is a membrane protein that transports calcium from the cytosol into the sarcoplasmic reticulum (SR) of muscle cells. The SR is a structure which stores calcium in muscle cells, similar to the smooth endoplasmic reticulum of other cells. SERCA is a calcium ATPase-type P-ATPase. It uses energy from ATP to actively transport calcium ions across the SR membrane.
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Discussion questions
- Summarise the article in your own words. Which single claim would you verify first, and why?
- Which claim in this article is most likely to be revised as the sources update? How would you check its current status?
- If two sources disagreed about one of these facts, what would you need in order to trust one over the other?
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