Lesson plan

Ski complex

The Ski complex (or Superkiller Complex) is a multi-protein complex found in many organisms including humans and yeast. In yeast, it is involved in the 3' end degradation of messenger RNAs. The Ski genes were first discovered due to mutations in yeast that led to an excessive expression of killer toxin.

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Article summary

The Ski complex (or Superkiller Complex) is a multi-protein complex found in many organisms including humans and yeast. In yeast, it is involved in the 3' end degradation of messenger RNAs. The Ski genes were first discovered due to mutations in yeast that led to an excessive expression of killer toxin.

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Discussion questions

  1. Summarise the article in your own words. Which single claim would you verify first, and why?
  2. Which claim in this article is most likely to be revised as the sources update? How would you check its current status?
  3. If two sources disagreed about one of these facts, what would you need in order to trust one over the other?

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