Spiperone
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Spiperone, also known as spiroperidol and sold under the brand name Spiropitan ( (JP) ) is a typical antipsychotic of the butyrophenone family related to haloperidol. It is approved for clinical use in Japan as a treatment for schizophrenia.
Spiperone, also known as spiroperidol and sold under the brand name Spiropitan ( (JP) ) is a typical antipsychotic of the butyrophenone family related to haloperidol. It is approved for clinical use in Japan as a treatment for schizophrenia.
Pharmacology
Pharmacodynamics
Spiperone interacts with various monoamine receptors. Additionally, spiperone was identified by compound screening to be an activator of Ca 2+ activated Cl − channels (CaCCs), thus a potential target for therapy of cystic fibrosis.
Chemistry
Derivatives
N-Methylspiperone (NMSP) is a derivative of spiperone that is used to study the dopamine and serotonin neurotransmitter system. Labeled with the radioisotope carbon-11, it can be used for positron emission tomography.
See also
Spirodecanone
References
Text derived from https://en.wikipedia.org/w/index.php?oldid=1333463059 under CC BY-SA 4.0; modifications have been made.