Lesson plan
SURF2
SURF2 is a protein which in humans is encoded by the SURF2 gene. SURF2 is a member of the surfeit gene family. The SURF2 molecule interacts with beta-1, 4-Gal-T3, uPAR, and WDR20. As part of the surfeit gene cluster, SURF2 is one of several tightly linked genes that do not share sequence similarity. SURF2 maps to human chromosome 9q34.2 and shares a bidirectional promoter with SURF1 on the opposite strand. A bidirectional promoter activity is expected in the intergenic region between SURF1 and SURF2, as seen in mice.
Article summary
SURF2 is a protein which in humans is encoded by the SURF2 gene. SURF2 is a member of the surfeit gene family. The SURF2 molecule interacts with beta-1, 4-Gal-T3, uPAR, and WDR20. As part of the surfeit gene cluster, SURF2 is one of several tightly linked genes that do not share sequence similarity. SURF2 maps to human chromosome 9q34.2 and shares a bidirectional promoter with SURF1 on the opposite strand. A bidirectional promoter activity is expected in the intergenic region between SURF1 and SURF2, as seen in mice.
Key claims
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Discussion questions
- Summarise the article in your own words. Which single claim would you verify first, and why?
- Which claim in this article is most likely to be revised as the sources update? How would you check its current status?
- If two sources disagreed about one of these facts, what would you need in order to trust one over the other?
Bibliography
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Key claims and bibliography are generated from the same tracked claims and sources as the article page.