TMLHE
≈ 1 min read
Names in other languages
No names in other languages are held for this entry yet.
Article bodies are English and are not machine-translated. A name in another language is not a translation of the article.
Trimethyllysine dioxygenase, mitochondrial is an enzyme that in humans is encoded by the TMLHE gene in chromosome X. Mutations in the TMLHE gene resulting in carnitine biosynthesis disruption have been associated with autism symptoms.
Trimethyllysine dioxygenase, mitochondrial is an enzyme that in humans is encoded by the TMLHE gene in chromosome X. Mutations in the TMLHE gene resulting in carnitine biosynthesis disruption have been associated with autism symptoms. N 6 ,N 6 ,N(6)-trimethyl-L-lysine + 2-oxoglutarate + O 2 = 3-hydroxy-N 6 ,N 6 ,N(6)-trimethyl-L-lysine + succinate + CO 2 and requires iron and L-ascorbate as co-factors.
Text derived from https://en.wikipedia.org/w/index.php?oldid=1378785426 under CC BY-SA 4.0; modifications have been made.