Top1
≈ 1 min read
Names in other languages
- DeutschTop1
- EnglishTop1
- EspañolTop1
- FrançaisTop1
- NederlandsTop1
- PortuguêsTop1
- srnTop1
- SvenskaTop1
Article bodies are English and are not machine-translated. A name in another language is not a translation of the article.
DNA topoisomerase 1 is an enzyme that in humans is encoded by the TOP1 gene. It is a DNA topoisomerase, an enzyme that catalyzes the transient breaking and rejoining of a single strand of DNA.
DNA topoisomerase 1 is an enzyme that in humans is encoded by the TOP1 gene. It is a DNA topoisomerase, an enzyme that catalyzes the transient breaking and rejoining of a single strand of DNA.
DNA repair
Exposure of human HeLA cells to UVB irradiation specifically stimulates the formation of covalent complexes between topoisomerase I and DNA. Topoisomerase I appears to have a direct role in nucleotide excision repair, a process that removes UVB-induced, and other, DNA damages.
Text derived from https://en.wikipedia.org/w/index.php?oldid=1369485247 under CC BY-SA 4.0; modifications have been made.