Devazepide
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Devazepide (L-364,718, MK-329) is benzodiazepine drug, but with quite different actions from most benzodiazepines, lacking affinity for GABA A receptors and instead acting as an CCK A receptor antagonist. It increases appetite and accelerates gastric emptying, and has been suggested as a potential treatment for a variety of common gastrointestinal problems including dyspepsia, gastroparesis and gastric reflux. It is also widely used in scientific research into the CCK A receptor.
Devazepide (L-364,718, MK-329) is benzodiazepine drug, but with quite different actions from most benzodiazepines, lacking affinity for GABA A receptors and instead acting as an CCK A receptor antagonist. It increases appetite and accelerates gastric emptying, and has been suggested as a potential treatment for a variety of common gastrointestinal problems including dyspepsia, gastroparesis and gastric reflux. It is also widely used in scientific research into the CCK A receptor. ==Synthesis== Devazepide is synthesised in a similar manner to other benzodiazepines such as lorazepam.
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