Lesson plan
Devazepide
Devazepide (L-364,718, MK-329) is benzodiazepine drug, but with quite different actions from most benzodiazepines, lacking affinity for GABA A receptors and instead acting as an CCK A receptor antagonist. It increases appetite and accelerates gastric emptying, and has been suggested as a potential treatment for a variety of common gastrointestinal problems including dyspepsia, gastroparesis and gastric reflux. It is also widely used in scientific research into the CCK A receptor.
Article summary
Devazepide (L-364,718, MK-329) is benzodiazepine drug, but with quite different actions from most benzodiazepines, lacking affinity for GABA A receptors and instead acting as an CCK A receptor antagonist. It increases appetite and accelerates gastric emptying, and has been suggested as a potential treatment for a variety of common gastrointestinal problems including dyspepsia, gastroparesis and gastric reflux. It is also widely used in scientific research into the CCK A receptor.
Key claims
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Discussion questions
- Summarise the article in your own words. Which single claim would you verify first, and why?
- Which claim in this article is most likely to be revised as the sources update? How would you check its current status?
- If two sources disagreed about one of these facts, what would you need in order to trust one over the other?
Bibliography
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Key claims and bibliography are generated from the same tracked claims and sources as the article page.