MARCO
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Names in other languages
- EspañolMarco
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Macrophage receptor with collagenous structure (MARCO) is a protein that in humans is encoded by the MARCO gene. MARCO is a class A scavenger receptor that is found on particular subsets of macrophages. Scavenger receptors are pattern recognition receptors (PRRs) found most commonly on immune cells. Their defining feature is that they bind to polyanions and modified forms of a type of cholesterol called low-density lipoprotein (LDL). MARCO is able to bind and phagocytose these ligands and pathogen-associated molecular patterns (PAMPs), leading to the clearance of pathogens and cell signaling events that lead to inflammation. As part of the innate immune system, MARCO clears, or scavenges, pathogens, which leads to inflammatory responses. The scavenger receptor cysteine-rich (SRCR) domain at the end of the extracellular side of MARCO binds ligands to activate the subsequent immune responses. MARCO expression on macrophages has been associated with tumor development and also with Alzheimer's disease, via decreased responses of cells when ligands bind to MARCO.
Marco may refer to:
People
Given name
Marco (actor) (born 19771), South Korean model and actor
Surname
Georg Marco (1863–1923), Romanian chess player of German origin Jindřich Marco (1921–2000), Czechoslovak photographer and numismatist Joseph Marco (born 1988), Filipino actor Kenny Marco (1947–2025), Canadian guitarist. María del Pilar Sinués y Navarro de Marco (1835–1893), Spanish writer Tomás Marco (born 19421), Spanish composer and writer on music
Places
Marco, Ceará, Brazil, a municipality Marco, New Zealand, a locality in the Taranaki Region Marco, Indiana, United States, an unincorporated town Marco, Missouri, United States, an unincorporated community Marco Island, Florida, United States, a city and an island
Science and technology
Mars Cube One (MarCO), a pair of small satellites which fly by Mars in 2018 MARCO, a macrophage receptor protein that in humans is encoded by the MARCO gene Mid-Atlantic Regional Council on the Ocean (MARCO) Marco, the official window manager of MATE Maia and Marco, one of an artificial intelligence sportscaster pair
Arts and entertainment
Marco (1973 film), an American adventure film directed by Seymour Robbie Marco (2024 film), an Indian Malayalam language film directed by Haneef Adeni Marco: 3000 Leagues in Search of Mother, a 1999 Japanese anime film Marco, the Invented Truth, a 2024 Spanish biographical drama film Marco (comics), a fictional character in the DC Comics universe Marco Pagot, the main protagonist in Porco Rosso Marco (Animorphs), one of the six main characters in the book series Animorphs Marco, a character in the animated family comedy film Chibi Maruko-chan: A Boy from Italy "Marco" (Better Call Saul), an episode of Better Call Saul Marco (Marco Borsato album), 1994 Marco (Marco Antonio Solís album), 1997 Museo de Arte Contemporáneo de Monterrey (MARCO), the Museum of Contemporary Art in Monterrey, Mexico
Other uses
F.C. Marco, a former football club from Marco de Canaveses, Portugal List of storms named Marco
See also
Marc'O (1927–2025), French writer, researcher, director, playwright and filmmaker Marko (disambiguation) Marcos Macro (disambiguation) Narco (disambiguation)
Text derived from https://en.wikipedia.org/w/index.php?oldid=1376696619 under CC BY-SA 4.0; modifications have been made.