STEAP3
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Metalloreductase STEAP3 is an enzyme that in humans is encoded by the STEAP3 gene. STEAP3 is a metalloreductase, capable of converting iron from an insoluble ferric (Fe 3+ ) to a soluble ferrous (Fe 2+ ) form. STEAP3 and other STEAP protein, with the exception of STEAP1, are predicted to contain a Di-nucleotide binding domain (Rossmann Fold). This has been shown using X-ray crystallography in the cases of STEAP3 and STEAP4 (PDB: 2VNS, 2VQ3 and 2YJZ).
Metalloreductase STEAP3 is an enzyme that in humans is encoded by the STEAP3 gene. STEAP3 is a metalloreductase, capable of converting iron from an insoluble ferric (Fe 3+ ) to a soluble ferrous (Fe 2+ ) form. STEAP3 and other STEAP protein, with the exception of STEAP1, are predicted to contain a Di-nucleotide binding domain (Rossmann Fold). This has been shown using X-ray crystallography in the cases of STEAP3 and STEAP4 (PDB: 2VNS, 2VQ3 and 2YJZ).
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